and pharmacological properties of Kigelia africana (Lam.) Balmkheera, Isopinnatal, Kigelin, Chemical constituents, Medicinal properties. Objective: Kigelia africana, a tropical tree, which has long been used in African . Analytical grade solvents (Fischer chemicals) were used for isolation and. cancer with drugs (pharmacotherapy) or with chemical compounds ( chemotherapy) in family comprises 21 species, of which Kigelia africana. (Lam. ) Benth is.

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The phytochemical components of Kigelia pinnata based on the preliminary extract screening. Flavonoids afrifana been shown to exhibit their actions through effects on membrane permeability, and by inhibition of membrane-bound enzymes such as the ATPase and phospholipase A2 Li et al.

Analysis of tocopherols by capillary supercritical fluid chromatography and mass spectrometry.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

Other activities of lapachol and its derivatives include the prevention against Schistosoma mansoni cercarial skin penetration, Biomphalaria glabrata infection as well as forestalling embryo alteration in rats Maganha et al. Antibacterial and antifungal compounds from Kigelia pinnata.

The absorbance at nm was monitored in presence of different concentrations of extracts. Finally, the remaining extracted plant material was extracted again for five days with methanol. The in vitro antioxidant activities of the plant extracts Figure 5 Fig. Phenylpropanoid and phenylethanoid derivatives from Kigelia pinnata D.

Identification of each component was carried out using the peak enrichment technique of reference compounds and as final confirmation of the peak identification by GC-MS, their spectral were compared with those of NIST library mass spectra. Influence of trans fatty acids on health. The tree is widely grown as an ornamental plant in tropical regions for its decorative flowers and unusual fruit that conceived the name ‘sausage tree’ Roodt, [ 44 ].

Lapachol has been reportedly isolated from the root of the plant previously Govindachari et al. Important heteronuclear multiple-bond correlations of compound 4 Click here to view. None, Conflict of Interest: The radical was protected from light. Received Oct 24; Accepted Nov Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assay.


Constituents of Kigelia pinnata. Foyer CH, Noctor G.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

It is due to the presence of high content of phenolics, which could be the most effective in protecting the body against various oxidative stressors. The hexanes extract caused inhibition of the opportunistic yeast; Cryptococcus neoformans Pinh. The objective of the current study has been identifying the constituents of K. Prostaglandins Leukot Essent Fatty Acids.

Effect of methanol extract of Kigelia africana on sperm motility and fertility in rats. Pharm Pharmacol Lett ;7: This study indicates that the ethyl acetate fraction of the plant root has high antioxidant activity against DPPH than the hexane and methanol extract.

The total phenolic content was also found to be higher in KPRE at 0. Antioxidant activity of Galloyl quinic derivatives isolated from Pistacia lentiscus leaves. The 13 C NMR indicated seven equivalent carbon chemical environments. Phytochemical screening of the plant extracts A small portion of the dry extract was used for the phytochemical screening for compounds including tannins, phlobatannins, flavonoids, terpenoids, alkaloids, cardiac glycosides, anthraquinone, saponins, and steroids in accordance with methods described by Harborne [ 21 ]Trease and Evans [ 50 ] and Sofowora [ 48 ] with minor modifications.

The reducing capacity of the extracts, another significant indicator of antioxidant activity was also found to be appreciable. Anti-inflammatory activity of verminoside from Kigelia africana and evaluation of cutaneous irritation in cell chemicalz and reconstituted human epidermis.

Therefore, the objective of the study was to identify phytochemicals that are present in the leave of Kigelia pinnata. The MS data is in agreement with literature data Heinrich et al. UV and IR spectroscopic techniques were used to carry out partial characterization of the oil and extracts. Total antioxidant activity in plant materials and its interest in food technology. Antioxidant activity measured in different solvent fractions obtained from Mentha spicata Linn.: Acetaminophen-induced liver damage in mice: The reducing powers of the extracts were evaluated according to the method of Oyaizu [ 40 ].


It could serve as intermediates in the manufacture of a variety of food ingredients. A leaf hydrocarbon from Syzygium jambos with stimulatory effects on the germination of Urediniospores of Puccinia psidii. Antidiarrhoeal activity of the aqueous leaf extract of Kigelia chemicaals experimental animal.

africzna The result is as shown in Table 1 Tab. Recent isolation from the fruits afforded a new phenylpropanoid derivative known as 6-p-coumaroyl-sucrose together with other known phenylpropanoid derivatives and flavonoid glycosides Gouda et al.

The phytochemical analysis conducted on the K. Higher absorbance of the reaction mixture indicates higher reductive potential.

New Constituents of Kigelia pinnata Leaves – SciAlert Responsive Version

This is an Open Access article distributed under the following Assignment of Rights http: It was suggested that the ability of the extract components to inhibit the synthesis of prostaglandins and other inflammatory mediators was responsible for its analgesic and anti-inflammatory activities Owolabi and Omogbai, Anticryptoccocal, antileishmanial, cannabinoid receptors, Kigelia africana, opioid receptors.

Chapman and Hall; In view of the various reports on the toxicity of elaidic acid, the therapeutic effect of the plant should be weighed along side its toxicity when administered in folk medicine. Royal Botanic Gardens, Kew, London, pp: Although an excess of Reactive Oxygen Species, ROS oxidative stress can result in non-controlled oxidation and damage of cellular structures such as DNA, protein kigelis membrane lipids.